Product Reviews
Take Action
Back
SIGN THE PETITION

Fight for Fair Finance

Tell the administration and Congress to stand up for the consumer watchdog that protects you from financial fraud and abuse.
Take Action
Why Do We Have Campaigns?
We're fighting to ensure you and your family can get a fair deal in the marketplace, especially on the choices that matter most: health care, privacy, automobiles, food, finances and more. Join our campaigns and together, we'll hold corporations and lawmakers accountable.

Should children take antipsychotic drugs?

For some kids with the drugs may help, but for many more they could be dangerous

Published: March 2012

Prescription medications called atypical antipsychotics, which include aripiprazole (Abilify), asenapine (Saphris), clozapine (Clozaril), iloperidone (Fanapt), olanzapine (Zyprexa), paliperidone (Invega), quetiapine (Seroquel), risperidone (Risperdal), and ziprasidone (Geodon), are given to children and teenagers to treat schizophrenia and bipolar disorder. They are also used to try and reduce aggression, irritability, and self-injuring behaviors associated with pervasive developmental disorders, including autism and Asperger syndrome, and disruptive behavior disorders. But prescribing these drugs to young people is controversial because they have not been well-studied, and the long-term safety and effectiveness for children and teens is unknown.

Studies in adults show that atypical antipsychotics can cause serious side effects, so long-term safety is a particular concern about their use in children. Some of the most worrisome side effects include uncontrollable movements and tremors that resemble Parkinson's disease (known as extrapyramidal symptoms), an increased risk of diabetes, substantial weight gain, and elevated cholesterol and triglyceride levels.

In addition, atypical antipsychotic drugs have been shown to increase the risk of premature death, primarily due to strokes, in older adults with dementia.

These risks have been studied primarily in adults—thus, the effects in children are not fully known at this time.

Because of the lack of evidence, we are unable choose a Best Buy atypical antipsychotic for use in kids with schizophrenia, bipolar disorder, pervasive developmental disorders, or disruptive behavior disorders.

Instead, our medical advisors recommend parents carefully weigh the potential risks of atypical antipsychotics against the potential benefits for their children. Kids with these disorders should receive comprehensive treatment that includes cognitive behavioral therapy, parent management training, and specialized educational programs, along with any potential drug therapy.

Deciding whether to use one of these medications at all, and if so, which one, should be done in conjunction with your child's doctor. Important considerations include cost, which can be substantial, potential side effects, and whether the medication has been shown to provide benefit for your child's most prominent condition or symptoms.

If your child has a co-existing condition—for example, ADHD or depression—you should make sure these are appropriately treated because this might improve your child's symptoms.

Editor's Note:

These materials are made possible by a grant from the state Attorney General Consumer and Prescriber Education Grant Program, which is funded by the multi-state settlement of consumer-fraud claims regarding the marketing of the prescription drug Neurontin (gabapentin).



E-mail Newsletters

FREE e-mail Newsletters!
Choose from cars, safety, health, and more!
Already signed-up?
Manage your newsletters here too.

More From Consumer Reports

WASHER REVIEWS
Best washing machines that cost $800 or lessVideo These workhorses of the laundry room won't break your budget.
FOOD SAFETY GUIDE
Special report: How safe is your ground beef?Video Recalls of bacteria-tainted ground beef are all too frequent.
SMARTPHONE REVIEWS
Hidden helpers in your phone are at your fingertips Smartphone functionality has zoomed way beyond driving directions.
PRESCRIPTION DRUG GUIDE
Why you shouldn't buy drugs from sites outside of the U.S. There are safer ways to save on your prescription drug costs.

Cars

Cars Build & Buy Car Buying Service
Save thousands off MSRP with upfront dealer pricing information and a transparent car buying experience.

See your savings

Mobile

Mobile Get Ratings on the go and compare
while you shop

Learn more