How to save on prescription drugs

Last reviewed: September 2009

Heavily advertised drugs usually aren’t the best first choice for health problems, according to the free Consumer Reports Best Buy Drugs program, which evaluates drug treatments for many common conditions based on effectiveness, safety, and cost.

Newer drugs are seldom more effective than older medications. Their shorter track record makes their safety less certain. And they almost always cost more, since they’re rarely available as generics. The table below shows how you could save up to $275 a month by using a comparable dose of a Best Buy Drug rather than a top brand-name drug. (People respond differently to drugs, so if you don’t get better with a recommended drug, talk with your doctor about switching.)

Time-tested treatments

Ask your doctor if you might benefit from any of these treatments:

Salsalate for arthritis

Once a commonly used prescription pain reliever, this chemical cousin of aspirin was eclipsed in the 1990s by the huge marketing push for other nonsteroidal anti-inflammatory drugs (NSAIDs). But it’s still an effective and inexpensive choice for pain relief, which is why it qualifies as a Consumer Reports Best Buy Drug.

Topical pain relievers

Although widely used in other countries, medicated creams and patches aren’t as popular in the U.S. That’s a shame because experts at the federal Agency for Healthcare Research and Quality recently concluded that topical NSAIDs were just as effective as pills at relieving the pain of osteoarthritis. Topical treatments can cause skin reactions, but pills affect the stomach and blood more. Over-the-counter creams include Aspercreme and Myoflex.

Diuretics for high blood pressure

An extensive body of research shows that diuretics such as hydrochlorothiazide (HydroDiuril and generic) or chlorothiazide (Diuril and generic) lower blood pressure just as well as newer and more expensive alternatives—including ACE inhibitors, beta-blockers, and calcium-channel blockers. And they are more likely to prevent heart failure and stroke. Yet many physicians still regularly prescribe those other drugs, especially for people with other cardiovascular risk factors, such as high blood sugar or cholesterol levels. A major study has confirmed that diuretics are superior, even for people in those groups.

Controlling conditions that aggravate asthma

Besides getting treatment, people with asthma should rid their environment of allergens. You can also ease symptoms by shedding excess pounds and treating sleep apnea.

Condition Brand-name or top-selling drug   CR Best Buy Drug Monthly savings Comments
Attention deficit/ hyperactivity disorder (ADHD) Strattera
One 18-mg pill per day $217
VS. Methylphenidate
Two 20-mg pills per day $40

$177

Make sure you or your child has an accurate diagnosis; ADHD drugs might be overused.
Constipation Amitiza
Two 8-mcg pills per day $220-294
VS. Polyethylene glycol powder
17 g per day $23

$197—271

Polyethylene glycol is available over the counter. Try a high-fiber diet, combined with a fiber supplement if necessary, before drugs.
Diabetes
(type 2)
Actos
One 30-mg pill per day $241
VS. Metformin
Two 1,000-mg pills per day $18

$223

Many people with diabetes need to take two drugs, and often metformin is a good first step.
Enlarged prostate Flomax
One 0.4-mg capsule per day $123
VS. Doxazosin
One 2-mg tablet per day $9

$114

To minimize side effects, start with a low dose. If that doesn’t help, consider another low-cost alpha-blocker.
Heartburn Nexium
One 20-mg pill per day $215
VS. Omeprazole
One 20-mg pill per day $15

$200

Omeprazole is available over the counter. See a doctor if you have heartburn two or more times per week for several weeks.
High LDL (bad) cholesterol Lipitor
One 10-mg pill per day $101
VS. Lovastatin
One 20-mg pill per day $18

$83

If you need to lower LDL by more than 30 percent, simvastatin can be a good option. If you have had a heart attack, have heart disease, or are at high risk, talk with your doctor about your drug options.
Insomnia Lunesta
One 2-mg pill at bedtime $93 for 15 pills
VS. Zolpidem
One 10-mg pill at bedtime $35 for 15 pills

$58

Don’t take sleeping pills every night for more than 10 days. Zolpidem varies in price for 15 pills. Shop around.
Osteoarthritis, joint pain Celebrex
Two 200-mg pills per day $296
VS. Ibuprofen
Three 400-mg pills per day $21

$275

Celebrex may be a good choice for people with a history of stomach problems if they are at low risk for heart disease or stroke.
NOTE: Prices are the national retail averages derived from data collected by Wolters Kluwer Health, Pharmaceutical Audit Suite.