Lansoprazole
(lan soe' pra zole)
(lan soe' pra zole)
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- We do not rely simply on drug package inserts and manufacturer claims.
- Our information about drug and safety, off-label uses, side effects and interactions is based on the best available clinical evidence -- the same information used by hospital pharmacists
Prevacid, Prevacid NapraPAC, Prevacid SoluTab, Prevpac
Lansoprazole is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from
the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the stomach produces too much acid,
such as Zollinger-Ellison syndrome. Lansoprazole is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Lansoprazole is in a class of medications called proton-pump inhibitors. It works by decreasing
the amount of acid made in the stomach.
Lansoprazole comes as a delayed-release (long-acting) capsule and granules to make a delayed-release solution (liquid) to
take by mouth. Lansoprazole is usually taken once a day, before eating. When taken in combination with other medications to
eliminate H. pylori, lansoprazole is taken twice a day (every 12 hours) or three times a day (every 8 hours) for 10 to 14 days. To help you remember
to take lansoprazole, take it around the same time every day. Follow the directions on your prescription label carefully,
and ask your doctor or pharmacist to explain any part you do not understand. Take lansoprazole exactly as directed. Do not
take more or less of it or take it more often than prescribed by your doctor.
The capsule should be swallowed whole. If you have difficulty swallowing capsules, lansoprazole capsules can be opened, and
the granules can be sprinkled on 1 tablespoon of applesauce, Ensure pudding, cottage cheese, yogurt, or strained pears and
swallowed immediately. The granules should not be chewed or crushed. The capsules can also be emptied into 2 ounces of orange
juice or tomato juice, mixed briefly, and swallowed immediately. Rinse the glass with some additional juice and drink immediately.
For patients who have a nasogastric tube, lansoprazole capsules can be opened and the granules mixed in 40 mL of apple juice.
The mixture should be injected through the nasogastric tube into the stomach. Then the tube should be flushed with some more
apple juice.
To use lansoprazole oral solution, empty the contents of a packet into a container containing 2 tablespoons of water. Stir
well and drink immediately. If any granules remain, add more water, stir, and drink immediately. Do not use liquids or foods
other than water. Do not crush or chew the granules.
Continue to take lansoprazole even if you feel well. Do not stop taking lansoprazole without talking to your doctor.
Lansoprazole may cause side effects. Tell your doctor if either of these symptoms is severe or does not go away:
- stomach pain
- diarrhea
Lansoprazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Before taking lansoprazole,
- tell your doctor and pharmacist if you are allergic to lansoprazole or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: ampicillin (Omnipen, Polycillin, Totacillin), digoxin (Lanoxin), ketoconazole (Nizoral), theophylline (Theo-bid, TheoDur), and vitamins containing iron. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking sucralfate (Carafate), take it at least 30 minutes after lansoprazole.
- tell your doctor if you have or have ever had liver or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking lansoprazole, call your doctor.
Unless your doctor tells you otherwise, continue your normal diet.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and
continue your dosing schedule. Do not take a double dose to make up for a missed one.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature
and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing,
call local emergency services at 911.
Keep all appointments with your doctor.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines
you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list
with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with
you in case of emergencies.











