Orphenadrine
(or fen' a dreen)
(or fen' a dreen)
What makes the information on ConsumerReportsHealth.org different?
- We do not rely simply on drug package inserts and manufacturer claims.
- Our information about drug and safety, off-label uses, side effects and interactions is based on the best available clinical evidence -- the same information used by hospital pharmacists
Invagesic, Norflex, Norgesic as a combination product containing Orphenadrine Citrate, Aspirin, and Caffeine, Norgesic Forte as a combination product containing Orphenadrine Citrate, Aspirin, and Caffeine
Orphenadrine is used with rest, physical therapy, and other measures to relieve pain and discomfort caused by strains, sprains,
and other muscle injuries.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Orphenadrine comes as a tablet and an extended-release tablet to take by mouth. It is usually taken twice a day. Do not cut,
crush, or chew the extended-release tablets; swallow them whole. Follow the directions on your prescription label carefully,
and ask your doctor or pharmacist to explain any part you do not understand. Take orphenadrine exactly as directed. Do not
take more or less of it or take it more often than prescribed by your doctor.
Orphenadrine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dry mouth
- drowsiness
- dizziness or lightheadedness
- upset stomach
- vomiting
- constipation
- difficulty urinating
- blurred vision
- headache
If you experience any of the following symptoms, call your doctor immediately:
- fast or irregular heartbeat
- fainting
- confusion
- hallucinations
- skin rash
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA)
MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
Before taking orphenadrine,
- tell your doctor and pharmacist if you are allergic to orphenadrine or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially amantadine (Symadine, Symmetrel), fluphenazine (Prolixin), haloperidol (Haldol), medications for colds or allergies, medications for depression, perphenazine (Trilafon), prochlorperazine (Compazine), promethazine (Phenergan), sedatives, sleeping pills, trifluoperazine (Stelazine), and vitamins.
- tell your doctor if you have or have ever had glaucoma; myasthenia gravis; ulcers; a urinary tract or intestinal blockage; an enlarged prostate; an irregular heartbeat; or liver, kidney, or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking orphenadrine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking orphenadrine.
- you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how orphenadine will affect you.
- remember that alcohol can add to the drowsiness caused by this drug.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and
continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Orphenadrine is also used occasionally to treat nighttime leg cramps. Talk to your doctor about the possible risks of using
this drug for your condition.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature
and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing,
call local emergency services at 911.
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines
you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list
with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with
you in case of emergencies.











