Prescription Drugs
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Captopril and Hydrochlorothiazide (kap' toe pril) (hye droe klor oh thye' a zide)
Other names: Capozide
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Do not take captopril and hydrochlorothiazide if you are pregnant. If you become pregnant while ... Full Alert
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Why is this medication prescribed?

The combination of captopril and hydrochlorothiazide is used to treat high blood pressure. Captopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly. Hydrochlorothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

How should this medication be used?

The combination of captopril and hydrochlorothiazide comes as a tablet to take by mouth. It is usually taken once or twice a day on an empty stomach, 1 hour before meals. To help you remember to take captopril and hydrochlorothiazide, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take captopril and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of captopril and hydrochlorothiazide and gradually increase your dose, not more than once every 6 to 8 weeks.

Captopril and hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take captopril and hydrochlorothiazide even if you feel well. Do not stop taking captopril and hydrochlorothiazide without talking to your doctor.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Capozide®
Last Revised January 07, 2003
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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