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Estrogen and Progestin (Oral Contraceptives) (ess' troe jen) (proe jes tin)
Other names: Alesse, Apri, Aviane, Brevicon, Demulen, Desogen, Estrostep, Estrostep Fe, Necon | More
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Why is this medication prescribed?

Oral contraceptives (birth-control pills) are used to prevent pregnancy. Estrogen and progestin are two female sex hormones. Combinations of estrogen and progestin work by preventing ovulation (the release of eggs from the ovaries). They also change the lining of the uterus (womb) to prevent pregnancy from developing and change the mucus at the cervix (opening of the uterus) to prevent sperm (male reproductive cells) from entering. Oral contraceptives are a very effective method of birth control, but they do not prevent the spread of human immunodeficiency virus [HIV, the virus that causes acquired immunodeficiency syndrome (AIDS)] and other sexually transmitted diseases.

Some brands of oral contraceptives are also used to treat acne in certain patients. Oral contraceptives treat acne by decreasing the amounts of certain natural substances that can cause acne.

One type of oral contraceptives (Yaz) is also used to relieve the symptoms of premenstrual dysphoric disorder (physical and emotional symptoms that occur before the menstrual period each month) in women who have chosen to use an oral contraceptive to prevent pregnancy.

How should this medication be used?

Oral contraceptives come in packets of 21, 28, or 91 tablets to take by mouth once a day, every day or almost every day of a regular cycle. To avoid nausea, take oral contraceptives with food or milk. Take your oral contraceptive at the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take your oral contraceptive exactly as directed. Do not take more or less of it, take it more often, or take it for a longer time than prescribed by your doctor.

Oral contraceptives come in many different brands. Different brands of oral contraceptives contain slightly different medications or doses, are taken in slightly different ways, and have different risks and benefits. Be sure that you know which brand of oral contraceptives you are using and exactly how you should use it. Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient and read it carefully.

If you have a 21-tablet packet, take one tablet daily for 21 days and then none for 7 days. Then start a new packet.

If you have a 28-tablet packet, take one tablet daily for 28 days. The last set of tablets in most 28 day packets are a different color. These tablets are reminder tablets. They do not contain any active ingredients but may contain iron. Taking one of these tablets every day will help you remember to start your next packet of birth control pills on time. One type of 28-tablet packet contains tablets that are all the same color. All of the tablets in this type of packet contain active ingredients. Whether your packet includes reminder tablets or only active tablets, you should take one tablet daily continuously for 28 days in the order specified in your packet. Start a new packet the day after you take your 28th tablet.

If you have a 91-day tablet packet, take one tablet daily for 91 days. Your packet will contain three trays of tablets. Start with the first tablet on the first tray and continue taking one tablet every day in the order specified on the packet until you have taken all of the tablets on all of the trays. The last set of tablets are a different color. These tablets may contain an inactive ingredient, or they may contain a very low dose of estrogen. Start your new packet the day after you take your 91st tablet.

Your doctor will tell you when you should start taking your oral contraceptive. Oral contraceptives are usually started on the first or fifth day of your menstrual period or on the first Sunday after or on which bleeding begins. Your doctor will also tell you whether you need to use another method of birth control during the first 7 days that you take your oral contraceptive and will help you choose a method. Follow these directions carefully.

You will probably experience withdrawal bleeding similar to a menstrual period while you are taking the inactive tablets or the low dose estrogen tablets or during the week that you do not take your oral contraceptive. If you are taking the type of packet that only contains active tablets, you will not experience any scheduled bleeding, but you may experience unexpected bleeding and spotting, especially at the beginning of your treatment. Be sure to start taking your new packet on schedule even if you are still bleeding.

You may need to use a backup method of birth control if you vomit or have diarrhea while you are taking an oral contraceptive. Talk to your doctor about this before you begin to take your oral contraceptive so that you can prepare a backup method of birth control in case it is needed. If you vomit or have diarrhea while you are taking an oral contraceptive, call your doctor to find out how long you should use the backup method.

If you have recently given birth, wait until 4 weeks after delivering to begin taking oral contraceptives. If you have had an abortion or miscarriage, talk to your doctor about when you should begin taking oral contraceptives.

Oral contraceptives will work only as long as they are taken regularly. Continue to take oral contraceptives every day even if you are spotting or bleeding, have an upset stomach, or do not think that you are likely to become pregnant. Do not stop taking oral contraceptives without talking to your doctor.

Are there other uses for this medicine?

Oral contraceptives are also sometimes used to treat heavy or irregular menstruation and endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes pain, heavy or irregular menstruation [periods], and other symptoms). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Alesse®
  • Apri®
  • Aviane®
  • Brevicon®
  • Demulen®
  • Desogen®
  • Estrostep®
  • Estrostep® Fe
  • Genora®
  • Jenest®
  • Levlen®
  • Levlite®
  • Levora®
  • Lo/Ovral®
  • Loestrin®
  • Loestrin® Fe
  • Low-Ogestrel®
  • Lybrel®
  • Microgestin®
  • Microgestin® Fe
  • Mircette®
  • Modicon®
  • Necon®
  • Nordette®
  • Norinyl®
  • Nortrel®
  • Ogestrel®
  • Ortho-Cept®
  • Ortho-Cyclen®
  • Ortho-Novum®
  • Ortho Tri-Cyclen®
  • Ovcon®
  • Ovral®
  • Seasonale®
  • Seasonique®
  • Tri-Levlen®
  • Tri-Norinyl®
  • Triphasil®
  • Trivora®
  • Yasmin®
  • Yaz®
  • Zovia®
Last Revised August 07, 2007
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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