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Estrogen Injection (ess' troe jen)
Other names: Delestrogen, DEPO-Estradiol, Premarin Intravenous
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Estrogen increases the risk that you will develop endometrial cancer (cancer of the lining of the ... Full Alert
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Why is this medication prescribed?

The estradiol cypionate and estradiol valerate forms of estrogen injection are used to treat hot flushes (hot flashes; sudden strong feelings of heat and sweating) and/or vaginal dryness, itching, and burning in women who are experiencing menopause (change of life; the end of monthly menstrual periods). However, women who need a medication only to treat vaginal dryness, itching, or burning should consider a different treatment. These forms of estrogen injection are also sometimes used to treat the symptoms of low estrogen in young women who do not produce enough estrogen naturally. The estradiol valerate form of estrogen injection is also sometimes used to relieve the symptoms of certain types of prostate (a male reproductive organ) cancer. The conjugated estrogens form of estrogen injection is used to treat abnormal vaginal bleeding that a doctor has decided is caused only by a problem with the amounts of certain hormones in the body. Estrogen injection is in a class of medications called hormones. It works by replacing estrogen that is normally produced by the body.

How should this medication be used?

The estradiol cypionate and estradiol valerate forms of long acting estrogen injection come as a liquid to inject into a muscle. These medications are usually injected by a health care professional once every 3-4 weeks. When the estradiol valerate form of estrogen injection is used to treat the symptoms of prostate cancer, it is usually injected by a health care professional once every 1-2 weeks.

The conjugated estrogens form of estrogen injection comes as a powder to mix with sterile water and inject into a muscle or vein. It is usually injected by a health care professional as a single dose. A second dose may be injected 6-12 hours after the first dose if it is needed to control vaginal bleeding.

If you are using estrogen injection to treat hot flushes, your symptoms should improve within 1-5 days after you receive the injection. Tell your doctor if your symptoms do not improve during this time.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Delestrogen®
  • DEPO-Estradiol®
  • Premarin Intravenous®
Last Revised January 04, 2006
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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