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Lamivudine (la mi' vyoo deen)
Other names: Combivir , Epivir, Epivir-HBV, Epzicom , Trizivir
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Lamivudine, when used alone or in combination with other antiviral medications, can cause serious ... Full Alert
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Why is this medication prescribed?

Lamivudine (Epivir) is used in combination with other medications to treat human immunodeficiency virus (HIV) infection in patients with acquired immunodeficiency syndrome (AIDS). Lamivudine is not a cure and may not decrease the number of HIV-related illnesses. Lamivudine does not prevent the spread of HIV to other people. Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors. It works by stopping the spread of the HIV and hepatitis B viruses.

How should this medication be used?

Lamivudine comes as a tablet and liquid to take by mouth. Lamivudine (Epivir) is usually taken every 12 hours (twice a day). Lamivudine (Epivir-HBV) is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lamivudine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take lamivudine even if you feel well. Do not stop taking lamivudine without talking to your doctor.

Are there other uses for this medicine?

Lamivudine is also used sometimes in combination with zidovudine (Retrovir, AZT) to treat health-care workers or other individuals exposed to HIV infection after accidental contact with HIV-contaminated blood, tissues, or other body fluids. Talk to your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Combivir® (as a combination product containing Lamivudine and Zidovudine)
  • Epivir®
  • Epivir-HBV®
  • Epzicom® (as a combination product containing Lamivudine and Abacavir Sulfate)
  • Trizivir® (as a combination product containing Lamivudine, Abacavir Sulfate, and Zidovudine)
Last Revised January 04, 2003
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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