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Lapatinib (la pa' ti nib)
Other names: Tykerb
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Why is this medication prescribed?

Lapatinib is used with capecitabine (Xeloda) to treat a certain type of advanced breast cancer in people who have already been treated with other chemotherapy medications. Lapatinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.

How should this medication be used?

Lapatinib comes as a tablet to take by mouth. It is usually taken once a day, at least 1 hour before or 1 hour after a meal. Take all of the tablets for your daily dose at this time each day. Lapatinib is usually taken once a day for 21 days before beginning the next treatment cycle. Take lapatinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lapatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Capecitabine is taken in combination with lapatinib, but on a different schedule. Be sure that you understand how and when to take capecitabine. Talk to your doctor and pharmacist if you have any questions about taking capecitabine.

Swallow the tablets whole; do not split, chew, or crush them.

Your doctor may gradually increase or decrease your dose of lapatinib during your treatment. This depends on how well the medication works for you and any side effects you may experience. Continue to take lapatinib even if you feel well. Do not stop taking lapatinib without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Tykerb®
Last Revised January 09, 2007
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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