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December 2008
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Zyrtec or Zantac? Beware of medication mix-ups

As much as 25 percent of drug errors—when someone gets the wrong prescription, say, or the wrong dosage—occur when the name of one drug looks or sounds like another. Poor penmanship, sloppy pronunciation, and look-alike labels make the problem worse.

In a report released earlier this year, U.S. Pharmacopeia, the official standards-setting body for medications in the U.S., reviewed more than 26,000 records of mix-ups involving similar drug names between 2003 and 2006. It found 3,170 confusing pairs, almost double the number cited in a 2004 report. In 384 cases, the error harmed the patient; in seven cases, it might have contributed to the patient’s death. The report’s authors suspect the real figures are higher, because incidents are underreported.

To check for sound-alike drug names, use USP’s free Drug Error Finder at www.usp.org/hqi/similarProducts/choosy.

Commonly confused drugs
Drug Confused with
Celebrex (celecoxib), for arthritis Celexa (citalopram), for depression
Catapres (clonidine), for hypertension Klonopin (clonazepam), for anxiety and seizures
Lamisil (terbinafine), for fungal infections Lamictal (lamotrigine), for seizures and bipolar disorder
Flagyl (metronidazole), an antibiotic Fortamet, Glucophage (metformin), for type 2 diabetes
Ditropan (oxybutynin), for overactive bladder Oxycontin (oxycodone), for pain
Prilosec (omeprazole), for ulcers and acid reflux Prozac (fluoxetine), for depression
Zoloft (sertraline), for depression Seroquel (quetiapine), for schizophrenia and bipolar disorder
Topamax (topiramate), for seizures Toprol XL (metoprolol), for hypertension and angina
Zetia (ezetimibe), for cholesterol Zestril (lisinopril), for hypertension
Zyrtec (cetirizine), for allergies Zantac (ranitidine), for ulcers and acid reflux
Each drug is listed by brand name and, in parentheses, generic name.
 
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