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Sitagliptin (sit a glip' tin)
Other names: Janumet , Januvia
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Why is this medication prescribed?

Sitagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Sitagliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

How should this medication be used?

Sitagliptin comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take sitagliptin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sitagliptin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Sitagliptin helps to control high blood sugar but does not cure diabetes. Continue to take sitagliptin even if you feel well. Do not stop taking sitagliptin without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Janumet® (as a combination product containing Sitagliptin and Metformin)
  • Januvia®
Last Revised January 10, 2007
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2009. All Rights Reserved.
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