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The metabolic syndrome

What is it?
The metabolic syndrome isn't a disease. It's a group of features that are linked to your body's metabolism. Your metabolism is the name given to all the chemical processes that happen in your body. The metabolic syndrome is also known as syndrome X or insulin resistance syndrome.1

The most common features of the metabolic syndrome are:1

If you have any of features of the metabolic syndrome, your doctor will tell you what to do to stay healthy. Losing weight and exercising regularly are important. Your doctor might advise you to make other changes in the way you live, and you might also need medication.

If you have metabolic syndrome, you are more likely to get type 2 diabetes, heart disease, a stroke and some other conditions.1

How common is it?
The metabolic syndrome is common. In the United States, more than 20 percent of people have it.2

What causes it?
If you have the metabolic syndrome, your body's insulin doesn't work as well as it should. This is called insulin resistance. It can be caused by:

  • Being overweight
  • Not getting enough exercise
  • Having certain genes.
How is it diagnosed?
There isn't any special test for the metabolic syndrome. And you don't get symptoms right away. The health problems it can cause, such as type 2 diabetes, happen over time.

Guidelines for doctors say that you might have the metabolic syndrome if you have three or more of the following things.1

  • Your waist measures 40 inches or more if you are a man, or 35 inches or more if you are a woman. If you are Asian-American, it is 35 inches or more if you a man, or 31 inches or more if you are a women.
  • The level of fats called triglycerides in your blood is 150 mg/dL or more before breakfast or you are taking medicine to lower your triglyceride). (The term mg/dL stands for milligrams per deciliter.)
  • Your level of good (HDL) cholesterol is less than 40 mg/dL if you are a man, or less than 50 mg/dL if you are a woman, or or you are taking medicine to raise your HDL cholesterol.
  • The level of glucose (sugar) in your blood is 100 mg/dL or more before breakfast or you are taking medicine to lower your blood sugar.
  • Your blood pressure is 130/85 or higher or you are taking medicine to lower your blood pressure. For more information, see High blood pressure.
To find out the levels of glucose, fats and cholesterol in your blood, your doctor will do a blood test.

How can it be prevented?
You can't change your genes. But you can:

  • Keep your weight down
  • Eat healthily
  • Exercise
  • Drink alcohol in moderation. That's one drink a day for women or two drinks a day for men. One drink is 1.5 ounces of hard liquor, 5 ounces of wine or 12 ounces of beer.
See your doctor if you think you might have the metabolic syndrome of any part of it.



Sources for the information on this page:
  1. Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation. 2005; 112: 2735-2752. 16157765
  2. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. Journal of the American Medical Association. 2002; 287: 356-359. 11790215
This information was last updated in Sep 04, 2008