If your gallstones cause symptoms, such as bouts of pain in your abdomen or inflammation of your gallbladder, the usual treatment is an operation to take out your gallbladder. With this treatment, there's a good chance you won't have any more symptoms. For example, more than 9 in 10 people who have this surgery because of painful gallstones stop getting the pain.1 2
It is very unlikely that you will die from gallstones. This can only happen if you get serious problems and you don't get treatment quickly. Such problems are rare. Also, people almost never die from gallstones in countries like the United States because you can get good treatment.3
You may worry about gallstones causing cancer. Cancer of your gallbladder is also rare. About 80 percent of people who have this kind of cancer also have gallstones. But we don't know if the stones caused the cancer. Most people with gallstones don't get gallbladder cancer.4
If your gallstones have not caused you any symptoms, doctors say you have silent gallstones. In this case, you probably won't get any problems in the future. So you probably won't need treatment.
In one study, only 2 in 100 people with silent gallstones started getting pain from them over the course of a year.5 In another study, just 3 in 100 people got problems from their stones over the course of 10 years.5
The pain you get in your abdomen from your gallstones is called biliary pain. If you have had an attack of this pain, you may get more. And you might need an operation to take out your gallbladder. This should stop you from getting more attacks.1 2
But other symptoms, like feeling sick to your stomach and getting indigestion, might not go away after your operation. This may be because gallstones were not the cause of these symptoms.1 6
Researchers have looked at what happens to people who get attacks of biliary pain if they don't have treatment. Here is what studies show:7
- About half of people who get an attack of this pain get another within one year.
- Some people have one or two attacks of biliary pain and then don't have any symptoms for many years. About 1 in 3 people who have an attack don't have another one for 10 years.
- In a year, 1 or 2 in 100 people who get attacks of biliary pain get a problem such as inflammation of their gallbladder.
- If you get attacks of biliary pain often, you will likely keep getting them often. If you only get attacks rarely, you will likely keep getting them rarely.
Your doctor will usually suggest an operation to take out your gallbladder. This should stop symptoms such as pain in your abdomen and fever. It should also stop you from getting more pain attacks.1 2
Most people who have an inflamed gallbladder find the pain either doesn't go away or comes back soon if they don't have treatment. About 1 in 3 people who don't have treatment for an inflamed gallbladder get the same problem, or another gallstone problem, within three months.7
Inflammation of your gallbladder can lead to serious problems. In about 1 in 10 people with this, the gallbladder bursts or starts to die (called gangrene).9 If this happens, you need emergency surgery. Without treatment, about 1 in 5 people die.10
Here are some other serious problems you can get from gallstones.9
If a stone stops bile from flowing properly, the bile can get infected.5 When this infection happens in the tube that carries bile to your bowel (your bile duct), it is called cholangitis.
This is serious. It causes pain in your abdomen, yellow skin and eyes (called jaundice) and a fever. But getting an infection of your bile duct is rare.9
This happens when a stone blocks lower down in your bile duct. The blockage can stop the flow of digestive juices from your pancreas. So it gets inflamed. Doctors call this pancreatitis.
About 1 in 20 people with painful gallstones get an inflamed pancreas.9 If this happens, you might need surgery.9
Your gallbladder sits near your bowel. So if your gallbladder gets very inflamed, it may stick to part of your bowel. This could make a hole in your bowel. Doctors call this a fistula.
You will probably need an operation to take out your gallbladder and fix the hole. But getting a hole in your bowel is rare.9
Fortunately not. You can live quite healthily without your gallbladder.
After your gallbladder is taken out your liver will carry on making bile. Bile is the digestive juice that is usually stored in the gallbladder until it's needed. When you eat the bile is pumped into your bowel to help digest your food. If you don't have a gallbladder, the bile will flow straight into your bowel more often.
Having more bile in the bowel can cause diarrhoea. About 1 in 100 people who have their gallbladder removed get diarrhoea.11
- Berger MY, Olde Hartemen TC, Bohnen AM. Abdominal symptoms: do they disappear after cholecystectomy? Surgical Endoscopy. 2003; 17: 1723-1728.
- Society for Surgery of the Alimentary Tract. Treatment of gallstone and gallbladder disease. Available at http://www.ssat.com/cgi-bin/chole7.cgi (accessed 8 September 2006).
- Cucchiaro G, Watters CR, Rossitch JC, et al. Deaths from gallstones: incidence and associated clinical factors. Annals of Surgery. 1989; 209: 149-151.
- American College of Gastroenterology. Gallstones. Available at http://www.acg.gi.org/patients (accessed 8 September 2006).
- Beckingham IJ. ABC of diseases of liver, pancreas, and biliary system: gallstone disease. BMJ. 2001; 322: 91-94.
- Bateson MC. Fortnightly review: gallbladder disease. BMJ. 1999; 318: 1745-1748 .
- Ransohoff DF, Gracie WA. Treatment of gallstones. Annals of Internal Medicine. 1993; 119: 606-619.
- Friedman GD. Natural history of asymptomatic and symptomatic gallstones. American Journal of Surgery. 1993; 165: 399-404.
- Lee SP, Ko CW. Gallstones. In: Alpers D H, et al (editors). Textbook of gastroenterology. 4th edition. Lippincott Williams & Wilkins, Philadelphia, U.S.A.; 2003.
- Isch JH, Finnernan JC, Nahrwold DL. Perforation of the gallbladder. American Journal of Gastroenterology. 1971; 55: 451-458.
- National Digestive Diseases Information Clearing House. Gallstones. Available at http://digestive.niddk.nih.gov/ddiseases/pubs/gallstones (accessed on 14 September 2006).
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This information is for educational use only, and is not a substitute for prompt professional medical advice. Readers should always consult a physician or other professional for advice and treatment. ©BMJ Publishing Group Limited 2008. All rights reserved. |











