While not a sales success, the GS is one of Lexus's best sedans which successfully melds luxury and sportiness. Engaging to drive yet with a supple ride. The GS 350 has a punchy V6 powertrain and is linked to a smooth transmission. Fuel economy, at 21 mpg on premium fuel, is not a standout however. Handling is quite agile and the ride is comfortable. The ultra-quiet cabin is beautifully finished and is quite accommodating but controls are frustrating to use.
Clearly, the car's Achilles Heel is its control layout, dominated by a giant display screen for audio, climate, navigation and communications functions, all manipulated by a mouselike multi-directional control knob on the center console. The system is an exercise in frustration, requires too much eye-off-the-road time and a delicate touch. It may work well when the car is parked but while driving it proves too distracting and aggravating. That's unfortunate because the GS is a decent car overall.