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    Can You Overcome 'Bad' Genes?

    Genes can increase risk for certain conditions, but many of the risk factors affecting longevity are modifiable.

    illustration of blue double helix with section in red Illustration: Consumer Reports, Getty Images

    In many cases, yes. If your parents and grandparents lived to be 100 and were in reasonably good health, you have a great shot at doing the same, says James E. Galvin, MD, a professor of neurology at the University of Miami Miller School of Medicine. But even if people in your family died at a young age from heart disease or developed early-onset Alzheimer’s, it won’t necessarily be the same for you.

    Think of your family history as a road map that can help you figure out where you are most resilient and most vulnerable, Galvin says.

    More on Healthy Aging

    Some gene variations significantly raise your risk for certain conditions: Variants in the BRCA gene make the development of breast cancer more likely, for example. And for diseases where early detection can lead to earlier treatment, such as heart disease and breast or prostate cancer, knowing you’re at increased risk can point your doctors to biomarkers they can check for. It can also help determine which conditions (if any) you should be screened for at a younger age than usual.

    In addition, your family health history can help you figure out where you might want to focus your own efforts as you get older. Lifestyle steps can significantly reduce your risk for a number of diseases—including many that run in families, such as Alzheimer’s, heart disease, and various cancers. (See the "What Can Help" sections throughout "How to Stay Healthy Longer" for more information on what to do.)

    In some cases, your genes may even help determine your treatment path and make you a good candidate for certain medical therapies, says Emily J. Rogalski, PhD, a cognitive neuroscientist at Northwestern University.

    Editor’s Note: This article also appeared in the September 2023 issue of Consumer Reports magazine.


    Kevin Loria

    Kevin Loria is a senior reporter covering health and science at Consumer Reports. He has been with CR since 2018, covering environmental health, food safety, infectious disease, fitness, and more. Previously, Kevin was a correspondent covering health, science, and the environment at Business Insider. Kevin lives in Washington, D.C., with his wife and children. Follow him on X: @kevloria.