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3 Best Disinfectant Wipes, Tested by Our Experts

We put popular Clorox and Lysol wipes to the test, as well as Amazon Basics, Target's Up&Up, Walmart's Great Value, and other brands

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Six brands of disinfecting wipes
If you're going to use disinfectants, you should use the best.
Photo: Scott Meadows/Consumer Reports

I’m at the tail end of my first winter with a toddler in day care, and I feel like I’ve survived an epic battle. Each (rare!) week in which all three human members of my family are healthy seems like a miracle. There’s one weapon I find myself tempted to wield: disinfectant wipes. After having the flu, two bouts of norovirus, COVID-19, and seemingly endless colds, I’m feeling a bit paranoid. 

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More on Cleaning

But disinfectant wipes should be used in moderation. Anna Soehl, a researcher at the Green Science Policy Institute, says they should be reserved for when there’s a risk of disease transmission, for example, after cleaning up vomit, blood, etc. “We really do not need to disinfect much at home,” she says. “Cleaning with plain soap and water should be sufficient.”

But sometimes your kid does barf in the car or your senior dog has a diarrhea explosion on the kitchen floor, and soap and water don’t quite cut it. In those instances, a disinfectant wipe or two can get the work started before you get a bucket of cleaning supplies to do the rest (or you call in a professional).

We tried six of the most popular disinfectant wipes on the market to see which ones cleaned the best—and had the least offensive smell—and which you shouldn’t bother with. (We didn’t look at how well the wipes disinfected.) Be sure to read our section on disinfectant safety, too. 

Best Everyday Essentials

Dish soaps, grout cleaners, upholstery cleaners, and other cleaning products are among the household basics that can make your days easier, more comfortable, and safer.

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We investigate, research, and test so you can choose with confidence.


Angela Lashbrook

Angela Lashbrook is a senior multimedia content creator at Consumer Reports. She has been with CR since 2021 and covers a wide range of topics, but she is particularly interested in anything health- or parenting-related. She lives with her husband, their son, and her dog, a Libra named Gordo.